Genetics of Icsi
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چکیده
منابع مشابه
Gonadotropin stimulation contributes to an increased incidence of epimutations in ICSI-derived mice.
We previously demonstrated that intracytoplasmic sperm injection (ICSI), a type of assisted reproductive technology (ART), can induce epimutations and/or epimutant phenotypes in somatic tissues of adult mice produced by this method. In the present study, we compared the occurrence of epimutations in mice produced by natural conception, ICSI and somatic cell nuclear transfer. Surprisingly, we ob...
متن کاملEmbryo quality and implantation rates are not influenced by total motile count values in an ICSI programme: a novel point of view.
Total motile count (TMC) is a useful tool for sperm evaluation, comprising both quantitative and motility parameters. Although frequently used, TMC has not yet been evaluated as a contributory variable for intracytoplasmic sperm injection (ICSI) cycles. In this study we evaluate the possible role of TMC as a prognostic parameter in cycles designated for ICSI. We also test the existence of a pos...
متن کاملWhich Is More Prominent in Recurrent Hydatidiform Mole, Ovum or Sperm?
Recurrent hydatidiform mole is defined as episodes of two molar pregnancies in a female. Often, complete moles onlyderive androgenic nuclear genome. We described two cases with repeated molar pregnancies attempted to preventfuture episodes by performing intracytoplasmic sperm injection (ICSI) and preimplantation genetic diagnosis (PGD)to assess genetic disorders. The first pat...
متن کاملA cytogenetic study of couples with recurrent spontaneous abortions and infertile patients with recurrent IVF/ICSI failure
PURPOSE This study was conducted to determine the frequency and contribution of chromosomal abnormalities in miscarriages and in couples with recurrent in vitro fertilization/intra cytoplasmic sperm injection (IVF/ICSI) failure. MATERIALS AND METHODS A total of 221 individuals; 79 with three or more recurrent spontaneous abortions and 142 with at least three IVF/ICSI failures. Chromosomal ana...
متن کاملIncreased prevalence of imprinting defects in patients with Angelman syndrome born to subfertile couples.
Recent case reports have suggested that infertility treatment with intracytoplasmic sperm injection (ICSI) may increase the risk of imprinting defects leading to Angelman syndrome (AS). Although imprinting defects account for only 4% of patients with AS, we have found four cases among 16 AS patients born to subfertile couples, who conceived with or without infertility treatment (25%; relative r...
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